Description
Oxandrolone
Oxadrolone, also known as Oxandrolone, is a synthetic anabolic-androgenic steroid (AAS). Here are some key points about Oxadrolone:
Anabolic effects: Oxandrolone promotes muscle growth and increases strength.
Androgenic effects: Oxadrolone has mild androgenic properties, which can lead to male characteristics such as deepening of the voice and facial hair growth.
Medical use: Oxandrolone is used to treat various medical conditions, including:
1. Muscle wasting diseases
2. Osteoporosis
3. Burns
4. Trauma
Athletic use: Oxadrolone sometimes also helps illicitly by athletes and bodybuilders to enhance performance and physique.
Chemical structure: Oxadrolone has a chemical structure similar to testosterone, but with a few key differences that affect its pharmacological properties.
Pharmacology
Oxadrolone is a synthetic anabolic-androgenic steroid (AAS) that works by:
1. Binding to androgen receptors: Oxadrolone binds to androgen receptors in muscle tissue, bone, and other organs, stimulating protein synthesis and nitrogen retention.
2. Increasing protein synthesis: Oxadrolone promotes protein production in muscle tissue, leading to increased muscle mass and strength.
3. Enhancing nitrogen retention: Oxadrolone helps maintain muscle mass by reducing nitrogen loss.
Medical Applications
Oxadrolone helps in treating various medical conditions, including:
1. Muscle wasting diseases: Oxadrolone also helps in treating muscle wasting diseases such as Duchenne muscular dystrophy.
2. Osteoporosis: Oxadrolone is used to treat osteoporosis, a condition characterized by brittle and porous bones.
3. Burns: Oxadrolone is used to aid in the recovery of burn patients by promoting wound healing and tissue repair.
4. Trauma: Oxadrolone also helps in the recovery of patients who have experienced trauma, such as fractures or surgery.
Athletic Use
Oxadrolone sometimes also helps illicitly by athletes and bodybuilders to:
1. Enhance performance: Oxadrolone also helps in improving athletic performance by increasing muscle mass, strength, and endurance.
2. Improve physique: Oxadrolone also helps in the enhancement of muscle growth and definition, leading to an improved physique.
Chemical Structure
Oxadrolone has a chemical structure similar to testosterone, but with a few key differences that affect its pharmacological properties. Specifically, Oxadrolone has a:
1. 2-oxa substitution: Oxadrolone has a 2-oxa substitution, which replaces the 2-carbon atom with an oxygen atom.
2. 17α-alkylation: Oxadrolone has a 17α-alkylation, which adds a methyl group to the 17α-carbon atom.
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