Description
Nandrolone Decanoate
Nandrolone Decanoate is a synthetic anabolic-androgenic steroid (AAS) used in veterinary medicine and, illicitly, in bodybuilding and athletics.
Here are some key points about it:
1. Anabolic effects: It promotes muscle growth and increases strength.
2. Androgenic effects: Ite has androgenic properties, which can lead to male characteristics such as deepening of the voice and facial hair growth.
3. Decanoate ester: The Decanoate ester extends the drug’s half-life, allowing for less frequent injections.
4. Veterinary use: It also helps in veterinary medicine to improve growth rate and feed efficiency in cattle.
5. Illicit use: Nandrolone Decanoate sometimes helps in illicitly by athletes and bodybuilders to enhance performance and physique.
Chemical Structure
It is a synthetic steroid hormone with the chemical name 19-nortestosterone 17β-decanoate. Its molecular formula is C28H44O3.
Pharmacology
It is an anabolic-androgenic steroid (AAS) that works by:
1. Binding to androgen receptors: It binds to androgen receptors in muscle tissue, bone, and other organs, stimulating protein synthesis and nitrogen retention.
2. Increasing protein synthesis: It promotes protein production in muscle tissue, leading to increased muscle mass and strength.
3. Enhancing nitrogen retention: Nandrolone Decanoate helps maintain muscle mass by reducing nitrogen loss.
Veterinary Applications
Nandrolone Decanoate is also used in veterinary medicine to:
1. Improve growth rate: It also helps in increasing growth rate and feed efficiency in cattle.
2. Enhance muscle mass: Nandrolone Decanoate also helps to increase muscle mass and improve carcass quality in cattle.
Illicit Use
It sometimes also help illicitly by athletes and bodybuilders to:
1. Enhance performance: It also helps in improving athletic performance by increasing muscle mass, strength, and endurance.
2. Improve physique: It also helps to enhance muscle growth and definition, leading to an improved physique.
Metabolism
Nandrolone Decanoate also metabolizes in the liver by enzymes such as 5α-reductase and 3α-hydroxysteroid dehydrogenase.
Pharmacokinetics
It has a pharmacokinetic profile characterized by:
1. Slow absorption: It also slowly absorbs into the bloodstream after intramuscular injection.
2. Long half-life: It has a half-life of approximately 7-10 days.
3. High bioavailability: Nandrolone Decanoate has high bioavailability, meaning that it absorbs and also uses a significant proportion of the dose.
Analytical Chemistry
It can be detected and quantified using various analytical techniques, including:
1. Gas chromatography-mass spectrometry (GC-MS).
2. Liquid chromatography-mass spectrometry (LC-MS).
3. High-performance liquid chromatography (HPLC).
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